Generic Name: naproxen (na-PROX-en)
Brand Name: Examples include Anaprox and Naprosyn
Anaprox is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, a heart attack, stroke). The risk may be greater if you already have heart problems or if you take Anaprox for a long time. Do not use Anaprox right before or after bypass heart surgery.
Anaprox may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.
Anaprox is used for:
Treating rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile arthritis. It is also used to treat tendonitis, bursitis, gout, menstrual cramps, or mild to moderate pain. It may also be used for other conditions as determined by your doctor.
Anaprox is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.
Do NOT use Anaprox if:
you are allergic to any ingredient in Anaprox
you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or another NSAID (eg, ibuprofen, celecoxib)
you have recently had or will be having bypass heart surgery
if you have severe kidney problems
you are in the last 3 months of pregnancy
you are taking another medicine that contains naproxen
Contact your doctor or health care provider right away if any of these apply to you.
Before using Anaprox:
Some medical conditions may interact with Anaprox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers, ulcerative colitis, Crohn disease)
if you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation
if you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk of any of these diseases
if you have poor health; dehydration or low fluid volume; low blood sodium levels; you are on a low-salt (sodium) diet; or you drink alcohol, smoke, or have a history of alcohol abuse
Some MEDICINES MAY INTERACT with Anaprox. Tell your health care provider if you are taking any other medicines, especially any of the following:
Anticoagulants (eg, warfarin), antiplatelet medicines (eg, clopidogrel), aspirin, corticosteroids (eg, prednisone), heparin, other NSAIDs (eg, ibuprofen), rivaroxaban, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
Probenecid because it may increase the risk of Anaprox’s side effects
Bisphosphonates (eg, alendronate), cyclosporine, hydantoins (eg, phenytoin), lithium, methotrexate, quinolones (eg, ciprofloxacin), sulfonamides (eg, sulfamethoxazole), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Anaprox
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Anaprox
This may not be a complete list of all interactions that may occur. Ask your health care provider if Anaprox may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Anaprox:
Use Anaprox as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Anaprox comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Anaprox refilled.
Take Anaprox by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach of bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
Take Anaprox with a full glass of water (8 oz [240 mL]) as directed by your doctor.
If you take antacids, cholestyramine, or sucralfate, ask your doctor or pharmacist how to take them with Anaprox.
If you miss a dose of Anaprox and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.